Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Diacylglycerol O-acyltransferase 2
(Homo sapiens (Human)) | BDBM323624
(US10188653, Example 13 | US9789110, 13)Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1ccc(cc1C)C(O)=O |r| Show InChI InChI=1S/C27H30N4O5/c1-3-35-23-8-4-5-9-24(23)36-22-7-6-12-31(17-22)27-29-15-21(16-30-27)25(32)28-14-20-11-10-19(26(33)34)13-18(20)2/h4-5,8-11,13,15-16,22H,3,6-7,12,14,17H2,1-2H3,(H,28,32)(H,33,34)/t22-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 45.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description
For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o... |
US Patent US9789110 (2017)
BindingDB Entry DOI: 10.7270/Q20G3N81 |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 2
(Homo sapiens (Human)) | BDBM323624
(US10188653, Example 13 | US9789110, 13)Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1ccc(cc1C)C(O)=O |r| Show InChI InChI=1S/C27H30N4O5/c1-3-35-23-8-4-5-9-24(23)36-22-7-6-12-31(17-22)27-29-15-21(16-30-27)25(32)28-14-20-11-10-19(26(33)34)13-18(20)2/h4-5,8-11,13,15-16,22H,3,6-7,12,14,17H2,1-2H3,(H,28,32)(H,33,34)/t22-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 45.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description
For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o... |
US Patent US10188653 (2019)
BindingDB Entry DOI: 10.7270/Q28G8NS4 |
More data for this
Ligand-Target Pair | |