Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitogen-activated protein kinase kinase kinase 14
(Homo sapiens (Human)) | BDBM50502744
(CHEMBL4524153)Show SMILES CCOc1nc2ccc(cc2n1-c1ccnc(N)n1)C#C[C@@](C)(O)c1ncc(C)o1 |r| Show InChI InChI=1S/C21H20N6O3/c1-4-29-20-25-15-6-5-14(7-9-21(3,28)18-24-12-13(2)30-18)11-16(15)27(20)17-8-10-23-19(22)26-17/h5-6,8,10-12,28H,4H2,1-3H3,(H2,22,23,26)/t21-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of NIK (unknown origin) using ATP as substrate by transcreener ADP assay based fluorescence correlation spectroscopic analysis |
ACS Med Chem Lett 10: 1260-1265 (2019)
Article DOI: 10.1021/acsmedchemlett.8b00658
BindingDB Entry DOI: 10.7270/Q2GF0XRG |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase D1
(Homo sapiens (Human)) | BDBM50502744
(CHEMBL4524153)Show SMILES CCOc1nc2ccc(cc2n1-c1ccnc(N)n1)C#C[C@@](C)(O)c1ncc(C)o1 |r| Show InChI InChI=1S/C21H20N6O3/c1-4-29-20-25-15-6-5-14(7-9-21(3,28)18-24-12-13(2)30-18)11-16(15)27(20)17-8-10-23-19(22)26-17/h5-6,8,10-12,28H,4H2,1-3H3,(H2,22,23,26)/t21-/m1/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of full length GST-tagged human PRKD1 expressed in Baculovirus expression system using ATP as substrate incubated for 1 to 2 hrs by transc... |
ACS Med Chem Lett 10: 1260-1265 (2019)
Article DOI: 10.1021/acsmedchemlett.8b00658
BindingDB Entry DOI: 10.7270/Q2GF0XRG |
More data for this
Ligand-Target Pair | |