Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 582.6 BDBM50562352

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NEDD8-activating enzyme E1 regulatory subunit (Homo sapiens (Human))	BDBM50562352 (CHEMBL4744561) Show SMILES CCOc1nc2cccc(C(=O)NCCc3c[nH]c4ccccc34)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NAE (unknown origin)-mediated neddylation assessed as suppression of cullin1-Nedd8 adduct formation preincubated for 10 mins followed b...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112964 BindingDB Entry DOI: 10.7270/Q2PN99CF
					More data for this Ligand-Target Pair