Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM228174
(1-{(R)-4-[4-(2-Ethoxy-pyrimidin-5-yl)-2-trifluorom...)Show SMILES CCOc1ncc(cn1)-c1cc(sc1C1CNCC(C)N1C(=O)Cn1cnc(n1)C(C)C)C(F)(F)F Show InChI InChI=1S/C23H28F3N7O2S/c1-5-35-22-28-8-15(9-29-22)16-6-18(23(24,25)26)36-20(16)17-10-27-7-14(4)33(17)19(34)11-32-12-30-21(31-32)13(2)3/h6,8-9,12-14,17,27H,5,7,10-11H2,1-4H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | 7.4 | n/a |
IDORSIA PHARMACEUTICALS LTD.
US Patent
| Assay Description
The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the... |
US Patent US10047080 (2018)
BindingDB Entry DOI: 10.7270/Q2JQ130F |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM228174
(1-{(R)-4-[4-(2-Ethoxy-pyrimidin-5-yl)-2-trifluorom...)Show SMILES CCOc1ncc(cn1)-c1cc(sc1C1CNCC(C)N1C(=O)Cn1cnc(n1)C(C)C)C(F)(F)F Show InChI InChI=1S/C23H28F3N7O2S/c1-5-35-22-28-8-15(9-29-22)16-6-18(23(24,25)26)36-20(16)17-10-27-7-14(4)33(17)19(34)11-32-12-30-21(31-32)13(2)3/h6,8-9,12-14,17,27H,5,7,10-11H2,1-4H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 299 | n/a | n/a | n/a | n/a | n/a | n/a |
IDORSIA PHARMACEUTICALS LTD.
US Patent
| Assay Description
Stock solutions of test compounds are made up at a concentration of 10 mM in DMSO, and serially diluted in PBS containing 0.5% BSA to concentrations ... |
US Patent US10047080 (2018)
BindingDB Entry DOI: 10.7270/Q2JQ130F |
More data for this
Ligand-Target Pair | |