Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 530.5 BDBM389810

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM389810 (US9951063, 129) Show SMILES CCOc1ncc(cn1)N1CCc2c(F)ccc(N3CCN([C@H](C)C3)C(=O)Cn3cnc4cccnc34)c2C1 Show InChI InChI=1S/C28H31FN8O2/c1-3-39-28-31-13-20(14-32-28)34-10-8-21-22(16-34)25(7-6-23(21)29)35-11-12-37(19(2)15-35)26(38)17-36-18-33-24-5-4-9-30-27(24)36/h4-7,9,13-14,18-19H,3,8,10-12,15-17H2,1-2H3/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				Bioorg Med Chem Lett 17: 3473-9 (2007) BindingDB Entry DOI: 10.7270/Q20R9RRK
					More data for this Ligand-Target Pair