Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 508.5 BDBM389812

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM389812 (US9951063, 131) Show SMILES CCOc1ncc(cn1)N1CCc2c(F)ccc(N3CCN([C@H](C)C3)C(=O)Cn3nc(C)nc3C)c2C1 Show InChI InChI=1S/C26H33FN8O2/c1-5-37-26-28-12-20(13-29-26)32-9-8-21-22(15-32)24(7-6-23(21)27)33-10-11-34(17(2)14-33)25(36)16-35-19(4)30-18(3)31-35/h6-7,12-13,17H,5,8-11,14-16H2,1-4H3/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24.3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				Bioorg Med Chem Lett 17: 3473-9 (2007) BindingDB Entry DOI: 10.7270/Q20R9RRK
					More data for this Ligand-Target Pair