Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50371486
(CHEMBL403254)Show SMILES CCS(=O)(=O)CCN([C@H](C)c1nc(C2CC2)c(C=C)n1-c1ccc(cc1)C#N)C(=O)Cc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C30H30F4N4O3S/c1-4-26-28(22-9-10-22)36-29(38(26)23-11-6-20(18-35)7-12-23)19(3)37(14-15-42(40,41)5-2)27(39)17-21-8-13-25(31)24(16-21)30(32,33)34/h4,6-8,11-13,16,19,22H,1,5,9-10,14-15,17H2,2-3H3/t19-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMC |
Bioorg Med Chem Lett 18: 608-13 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.072
BindingDB Entry DOI: 10.7270/Q2668F1D |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50371486
(CHEMBL403254)Show SMILES CCS(=O)(=O)CCN([C@H](C)c1nc(C2CC2)c(C=C)n1-c1ccc(cc1)C#N)C(=O)Cc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C30H30F4N4O3S/c1-4-26-28(22-9-10-22)36-29(38(26)23-11-6-20(18-35)7-12-23)19(3)37(14-15-42(40,41)5-2)27(39)17-21-8-13-25(31)24(16-21)30(32,33)34/h4,6-8,11-13,16,19,22H,1,5,9-10,14-15,17H2,2-3H3/t19-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMC in presence of plasma |
Bioorg Med Chem Lett 18: 608-13 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.072
BindingDB Entry DOI: 10.7270/Q2668F1D |
More data for this
Ligand-Target Pair | |