Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50371504
(CHEMBL403194)Show SMILES CCS(=O)(=O)CCN([C@H](C)c1nc(C2CC2)c(n1-c1ccc(cc1)C#N)C(F)(F)F)C(=O)Cc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C29H27F7N4O3S/c1-3-44(42,43)13-12-39(24(41)15-19-6-11-23(30)22(14-19)28(31,32)33)17(2)27-38-25(20-7-8-20)26(29(34,35)36)40(27)21-9-4-18(16-37)5-10-21/h4-6,9-11,14,17,20H,3,7-8,12-13,15H2,1-2H3/t17-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMC |
Bioorg Med Chem Lett 18: 608-13 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.072
BindingDB Entry DOI: 10.7270/Q2668F1D |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50371504
(CHEMBL403194)Show SMILES CCS(=O)(=O)CCN([C@H](C)c1nc(C2CC2)c(n1-c1ccc(cc1)C#N)C(F)(F)F)C(=O)Cc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C29H27F7N4O3S/c1-3-44(42,43)13-12-39(24(41)15-19-6-11-23(30)22(14-19)28(31,32)33)17(2)27-38-25(20-7-8-20)26(29(34,35)36)40(27)21-9-4-18(16-37)5-10-21/h4-6,9-11,14,17,20H,3,7-8,12-13,15H2,1-2H3/t17-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMC in presence of plasma |
Bioorg Med Chem Lett 18: 608-13 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.072
BindingDB Entry DOI: 10.7270/Q2668F1D |
More data for this
Ligand-Target Pair | |