Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM101358
(US9695151, 24 | US9695151, 25)Show SMILES CCS(=O)(=O)N1CCCC(C1)Nc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C22H27ClN4O3S/c1-4-31(29,30)26-9-5-6-16(14-26)25-17-11-18(13-24-12-17)27-21(28)19-8-7-15(23)10-20(19)22(27,2)3/h7-8,10-13,16,25H,4-6,9,14H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | n/a | 352 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... |
US Patent US9695151 (2017)
BindingDB Entry DOI: 10.7270/Q2KD1W22 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM101358
(US9695151, 24 | US9695151, 25)Show SMILES CCS(=O)(=O)N1CCCC(C1)Nc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C22H27ClN4O3S/c1-4-31(29,30)26-9-5-6-16(14-26)25-17-11-18(13-24-12-17)27-21(28)19-8-7-15(23)10-20(19)22(27,2)3/h7-8,10-13,16,25H,4-6,9,14H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | n/a | 1.39E+4 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... |
US Patent US9695151 (2017)
BindingDB Entry DOI: 10.7270/Q2KD1W22 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM101358
(US9695151, 24 | US9695151, 25)Show SMILES CCS(=O)(=O)N1CCCC(C1)Nc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C22H27ClN4O3S/c1-4-31(29,30)26-9-5-6-16(14-26)25-17-11-18(13-24-12-17)27-21(28)19-8-7-15(23)10-20(19)22(27,2)3/h7-8,10-13,16,25H,4-6,9,14H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | n/a | 443 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... |
US Patent US9695151 (2017)
BindingDB Entry DOI: 10.7270/Q2KD1W22 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM101358
(US9695151, 24 | US9695151, 25)Show SMILES CCS(=O)(=O)N1CCCC(C1)Nc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C22H27ClN4O3S/c1-4-31(29,30)26-9-5-6-16(14-26)25-17-11-18(13-24-12-17)27-21(28)19-8-7-15(23)10-20(19)22(27,2)3/h7-8,10-13,16,25H,4-6,9,14H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | n/a | 3.80E+4 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... |
US Patent US9695151 (2017)
BindingDB Entry DOI: 10.7270/Q2KD1W22 |
More data for this Ligand-Target Pair | |