Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 314.3 BDBM50401598

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50401598 (CHEMBL2203835) Show SMILES CCS(=O)(=O)Nc1ccc(-c2ccc(C#N)n2C)c(c1)C#N Show InChI InChI=1S/C15H14N4O2S/c1-3-22(20,21)18-12-4-6-14(11(8-12)9-16)15-7-5-13(10-17)19(15)2/h4-8,18H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity against progesterone receptor in human T47D cells by alkaline phosphatase assay				Bioorg Med Chem Lett 22: 7119-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.077 BindingDB Entry DOI: 10.7270/Q2S183NW
					More data for this Ligand-Target Pair