Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 349.4 BDBM50163591

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50163591 (2-(3,4-Dimethoxy-phenyl)-1-(3-ethyl-2-methyl-quino...) Show SMILES CCc1cc2cc(ccc2nc1C)C(=O)Cc1ccc(OC)c(OC)c1 Show InChI InChI=1S/C22H23NO3/c1-5-16-12-18-13-17(7-8-19(18)23-14(16)2)20(24)10-15-6-9-21(25-3)22(11-15)26-4/h6-9,11-13H,5,10H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1				J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017
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