Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Isoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402]
(Homo sapiens (Human)) | BDBM32493
(aryl piperidine, 9i)Show SMILES CCc1ccc(o1)C(=O)Nc1cccc(C)c1N1CCC2(CC1)OCCO2 Show InChI InChI=1S/C21H26N2O4/c1-3-16-7-8-18(27-16)20(24)22-17-6-4-5-15(2)19(17)23-11-9-21(10-12-23)25-13-14-26-21/h4-8H,3,9-14H2,1-2H3,(H,22,24) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
| Assay Description
Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a... |
Bioorg Med Chem Lett 19: 3344-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.086
BindingDB Entry DOI: 10.7270/Q2ST7N67 |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM32493
(aryl piperidine, 9i)Show SMILES CCc1ccc(o1)C(=O)Nc1cccc(C)c1N1CCC2(CC1)OCCO2 Show InChI InChI=1S/C21H26N2O4/c1-3-16-7-8-18(27-16)20(24)22-17-6-4-5-15(2)19(17)23-11-9-21(10-12-23)25-13-14-26-21/h4-8H,3,9-14H2,1-2H3,(H,22,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
| Assay Description
Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a... |
Bioorg Med Chem Lett 19: 3344-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.086
BindingDB Entry DOI: 10.7270/Q2ST7N67 |
More data for this
Ligand-Target Pair | |