Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human)) | BDBM286272
(5-{[(2S,5R)-2,5-dimethyl-4-(3,3,3-trifluoropropyl)...)Show SMILES CCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCC(F)(F)F)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C23H32F4N8O/c1-6-17-28-9-16(24)20(29-17)30-19-15-12-35(22(4,5)18(15)31-32-19)21(36)34-11-13(2)33(10-14(34)3)8-7-23(25,26)27/h9,13-14H,6-8,10-12H2,1-5H3,(H2,28,29,30,31,32)/t13-,14+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| 31.5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
PFIZER INC.
US Patent
| Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe... |
US Patent US9518060 (2016)
BindingDB Entry DOI: 10.7270/Q2ZK5JPN |
More data for this
Ligand-Target Pair | |
Protein kinase C beta type Isoform 2
(Homo sapiens (Human)) | BDBM286272
(5-{[(2S,5R)-2,5-dimethyl-4-(3,3,3-trifluoropropyl)...)Show SMILES CCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCC(F)(F)F)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C23H32F4N8O/c1-6-17-28-9-16(24)20(29-17)30-19-15-12-35(22(4,5)18(15)31-32-19)21(36)34-11-13(2)33(10-14(34)3)8-7-23(25,26)27/h9,13-14H,6-8,10-12H2,1-5H3,(H2,28,29,30,31,32)/t13-,14+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 31.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein kinase C beta type
(Homo sapiens (Human)) | BDBM286272
(5-{[(2S,5R)-2,5-dimethyl-4-(3,3,3-trifluoropropyl)...)Show SMILES CCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCC(F)(F)F)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C23H32F4N8O/c1-6-17-28-9-16(24)20(29-17)30-19-15-12-35(22(4,5)18(15)31-32-19)21(36)34-11-13(2)33(10-14(34)3)8-7-23(25,26)27/h9,13-14H,6-8,10-12H2,1-5H3,(H2,28,29,30,31,32)/t13-,14+/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 31.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q28S4T3T |
More data for this
Ligand-Target Pair | |