Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 518.0 BDBM50209206Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eyes absent homolog 3 (Homo sapiens (Human))	BDBM50209206 ((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodopheny...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1 Show InChI InChI=1S/C17H12I2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
CHILDREN HOSPITAL MEDICAL CENTER US Patent					Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....				US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ
					More data for this Ligand-Target Pair
Eyes absent homolog 3 (Homo sapiens (Human))	BDBM50209206 ((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodopheny...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1 Show InChI InChI=1S/C17H12I2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
GNF					Assay Description The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut...				Bioorg Med Chem Lett 16: 5488-92 (2006) BindingDB Entry DOI: 10.7270/Q2ZK5JZ7
					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 5 (Homo sapiens (Human))	BDBM50209206 ((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodopheny...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1 Show InChI InChI=1S/C17H12I2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins				Bioorg Med Chem Lett 17: 3122-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.042 BindingDB Entry DOI: 10.7270/Q2M04534
					More data for this Ligand-Target Pair