Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 418.5 BDBM50428026

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428026 (CHEMBL1444402) Show SMILES CCn1c(SCC(=O)Nc2nc3ccccc3s2)nc2CC(C)Sc2c1=O Show InChI InChI=1S/C18H18N4O2S3/c1-3-22-16(24)15-12(8-10(2)26-15)20-18(22)25-9-14(23)21-17-19-11-6-4-5-7-13(11)27-17/h4-7,10H,3,8-9H2,1-2H3,(H,19,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair