Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM286037
(N-(2-(3-Chlorophenyl)-1-ethyl-1H-indol-5-yl)-2-(di...)Show SMILES CCn1c(cc2cc(NC(=O)c3cc(CNC(=O)C(C)(C)F)cnc3C(F)F)ccc12)-c1cccc(Cl)c1 Show InChI InChI=1S/C28H26ClF3N4O2/c1-4-36-22-9-8-20(12-18(22)13-23(36)17-6-5-7-19(29)11-17)35-26(37)21-10-16(14-33-24(21)25(30)31)15-34-27(38)28(2,3)32/h5-14,25H,4,15H2,1-3H3,(H,34,38)(H,35,37) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 3.54 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.
US Patent
| Assay Description
mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each... |
US Patent US10081629 (2018)
BindingDB Entry DOI: 10.7270/Q20K2BMF |
More data for this
Ligand-Target Pair | |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM286037
(N-(2-(3-Chlorophenyl)-1-ethyl-1H-indol-5-yl)-2-(di...)Show SMILES CCn1c(cc2cc(NC(=O)c3cc(CNC(=O)C(C)(C)F)cnc3C(F)F)ccc12)-c1cccc(Cl)c1 Show InChI InChI=1S/C28H26ClF3N4O2/c1-4-36-22-9-8-20(12-18(22)13-23(36)17-6-5-7-19(29)11-17)35-26(37)21-10-16(14-33-24(21)25(30)31)15-34-27(38)28(2,3)32/h5-14,25H,4,15H2,1-3H3,(H,34,38)(H,35,37) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 12.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.
US Patent
| Assay Description
mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each... |
US Patent US10081629 (2018)
BindingDB Entry DOI: 10.7270/Q20K2BMF |
More data for this
Ligand-Target Pair | |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM286037
(N-(2-(3-Chlorophenyl)-1-ethyl-1H-indol-5-yl)-2-(di...)Show SMILES CCn1c(cc2cc(NC(=O)c3cc(CNC(=O)C(C)(C)F)cnc3C(F)F)ccc12)-c1cccc(Cl)c1 Show InChI InChI=1S/C28H26ClF3N4O2/c1-4-36-22-9-8-20(12-18(22)13-23(36)17-6-5-7-19(29)11-17)35-26(37)21-10-16(14-33-24(21)25(30)31)15-34-27(38)28(2,3)32/h5-14,25H,4,15H2,1-3H3,(H,34,38)(H,35,37) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 12.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.
US Patent
| Assay Description
mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each... |
US Patent US10081629 (2018)
BindingDB Entry DOI: 10.7270/Q20K2BMF |
More data for this
Ligand-Target Pair | |