Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Substance-P receptor
(Homo sapiens (Human)) | BDBM106974
(US8592454, 25)Show SMILES CN([C@@H]1CCN(C[C@H]1c1ccc(Cl)c(Cl)c1)C(=O)C1CCN(CC1)C(C)=O)C(=O)N(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C30H32Cl2F6N4O3/c1-17(43)41-9-6-18(7-10-41)27(44)42-11-8-26(23(16-42)19-4-5-24(31)25(32)12-19)40(3)28(45)39(2)22-14-20(29(33,34)35)13-21(15-22)30(36,37)38/h4-5,12-15,18,23,26H,6-11,16H2,1-3H3/t23-,26+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 0.0310 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Radioligand receptor binding inhibitory assay using human NK receptor. |
US Patent US8592454 (2013)
BindingDB Entry DOI: 10.7270/Q2XD10B0 |
More data for this
Ligand-Target Pair | |
Substance-K receptor
(Homo sapiens (Human)) | BDBM106974
(US8592454, 25)Show SMILES CN([C@@H]1CCN(C[C@H]1c1ccc(Cl)c(Cl)c1)C(=O)C1CCN(CC1)C(C)=O)C(=O)N(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C30H32Cl2F6N4O3/c1-17(43)41-9-6-18(7-10-41)27(44)42-11-8-26(23(16-42)19-4-5-24(31)25(32)12-19)40(3)28(45)39(2)22-14-20(29(33,34)35)13-21(15-22)30(36,37)38/h4-5,12-15,18,23,26H,6-11,16H2,1-3H3/t23-,26+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Radioligand receptor binding inhibitory assay using human NK receptor. |
US Patent US8592454 (2013)
BindingDB Entry DOI: 10.7270/Q2XD10B0 |
More data for this
Ligand-Target Pair | |
Neuromedin-K receptor
(Homo sapiens (Human)) | BDBM106974
(US8592454, 25)Show SMILES CN([C@@H]1CCN(C[C@H]1c1ccc(Cl)c(Cl)c1)C(=O)C1CCN(CC1)C(C)=O)C(=O)N(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C30H32Cl2F6N4O3/c1-17(43)41-9-6-18(7-10-41)27(44)42-11-8-26(23(16-42)19-4-5-24(31)25(32)12-19)40(3)28(45)39(2)22-14-20(29(33,34)35)13-21(15-22)30(36,37)38/h4-5,12-15,18,23,26H,6-11,16H2,1-3H3/t23-,26+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Radioligand receptor binding inhibitory assay using human NK receptor. |
US Patent US8592454 (2013)
BindingDB Entry DOI: 10.7270/Q2XD10B0 |
More data for this
Ligand-Target Pair | |