Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 476.4 BDBM50544809

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50544809 (CHEMBL4632719) Show SMILES CN([C@@H]1CCO[C@@H](C1)c1nnc([nH]1)-c1cnc2COCCn12)C(=O)c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C22H23F3N6O3/c1-30(21(32)13-3-2-4-14(9-13)22(23,24)25)15-5-7-34-17(10-15)20-27-19(28-29-20)16-11-26-18-12-33-8-6-31(16)18/h2-4,9,11,15,17H,5-8,10,12H2,1H3,(H,27,28,29)/t15-,17+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	102	n/a	n/a	n/a	n/a
Lilly China Research and Development Center (LCRDC) Curated by ChEMBL					Assay Description Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126857 BindingDB Entry DOI: 10.7270/Q2154MMP
					More data for this Ligand-Target Pair