Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 422.5 BDBM50101562

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50101562 (1-(1,2-Diphenyl-ethyl)-1-methyl-3-(4-phenoxy-pheny...) Show SMILES CN(C(Cc1ccccc1)c1ccccc1)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C28H26N2O2/c1-30(27(23-13-7-3-8-14-23)21-22-11-5-2-6-12-22)28(31)29-24-17-19-26(20-18-24)32-25-15-9-4-10-16-25/h2-20,27H,21H2,1H3,(H,29,31)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Neuropeptide Y5 Receptor.				J Med Chem 44: 2344-56 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J56
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50101562 (1-(1,2-Diphenyl-ethyl)-1-methyl-3-(4-phenoxy-pheny...) Show SMILES CN(C(Cc1ccccc1)c1ccccc1)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C28H26N2O2/c1-30(27(23-13-7-3-8-14-23)21-22-11-5-2-6-12-22)28(31)29-24-17-19-26(20-18-24)32-25-15-9-4-10-16-25/h2-20,27H,21H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Neuropeptide Y1 Receptor.				J Med Chem 44: 2344-56 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J56
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50101562 (1-(1,2-Diphenyl-ethyl)-1-methyl-3-(4-phenoxy-pheny...) Show SMILES CN(C(Cc1ccccc1)c1ccccc1)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C28H26N2O2/c1-30(27(23-13-7-3-8-14-23)21-22-11-5-2-6-12-22)28(31)29-24-17-19-26(20-18-24)32-25-15-9-4-10-16-25/h2-20,27H,21H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Neuropeptide Y2 Receptor.				J Med Chem 44: 2344-56 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J56
					More data for this Ligand-Target Pair