Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 509.5 BDBM589116

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM589116 ((E)-4-(dimethylamino)- 1-(10-((4-((4- methylbenzyl...) Show SMILES CN(C)C\C=C\C(=O)N1CCOc2c1ccc1ncnc(Nc3ccc(OCc4ccc(C)cc4)cc3)c21 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay for the inhibition of EGFR and HER2 kinase activity by small molecular compounds was carried out using the method as follows:1) Dilution of...				Citation and Details BindingDB Entry DOI: 10.7270/Q2X63RSM
					More data for this Ligand-Target Pair