Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50135639
(Benzofuran-2-carboxylic acid (2-benzylsulfanyl-phe...)Show SMILES CN(C)CCCN(C(=O)c1cc2ccccc2o1)c1ccccc1SCc1ccccc1 Show InChI InChI=1S/C27H28N2O2S/c1-28(2)17-10-18-29(27(30)25-19-22-13-6-8-15-24(22)31-25)23-14-7-9-16-26(23)32-20-21-11-4-3-5-12-21/h3-9,11-16,19H,10,17-18,20H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY from NPYY2 receptor (unknown origin) |
Bioorg Med Chem Lett 24: 430-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.061
BindingDB Entry DOI: 10.7270/Q2H133HQ |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50135639
(Benzofuran-2-carboxylic acid (2-benzylsulfanyl-phe...)Show SMILES CN(C)CCCN(C(=O)c1cc2ccccc2o1)c1ccccc1SCc1ccccc1 Show InChI InChI=1S/C27H28N2O2S/c1-28(2)17-10-18-29(27(30)25-19-22-13-6-8-15-24(22)31-25)23-14-7-9-16-26(23)32-20-21-11-4-3-5-12-21/h3-9,11-16,19H,10,17-18,20H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity against SMS-KAN cell membranes endogenously expressing Neuropeptide Y receptor type 2 using [125I]-PYY as radioligand |
Bioorg Med Chem Lett 13: 2883-5 (2003)
BindingDB Entry DOI: 10.7270/Q2F47NJQ |
More data for this
Ligand-Target Pair | |