Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 414.5 BDBM50135651

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50135651 (Benzo[b]thiophene-2-carboxylic acid biphenyl-2-yl-...) Show SMILES CN(C)CCCN(C(=O)c1cc2ccccc2s1)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C26H26N2OS/c1-27(2)17-10-18-28(26(29)25-19-21-13-6-9-16-24(21)30-25)23-15-8-7-14-22(23)20-11-4-3-5-12-20/h3-9,11-16,19H,10,17-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity against SMS-KAN cell membranes endogenously expressing Neuropeptide Y receptor type 2 using [125I]-PYY as radioligand				Bioorg Med Chem Lett 13: 2883-5 (2003) BindingDB Entry DOI: 10.7270/Q2F47NJQ
					More data for this Ligand-Target Pair