Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 510.5 BDBM50323887

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50323887 (3-(2-(dimethylamino)ethoxy)-4-oxo-2-(4-(quinolin-2...) Show SMILES CN(C)CCOc1c(oc2c(cccc2c1=O)C(O)=O)-c1ccc(OCc2ccc3ccccc3n2)cc1 Show InChI InChI=1S/C30H26N2O6/c1-32(2)16-17-36-29-26(33)23-7-5-8-24(30(34)35)28(23)38-27(29)20-11-14-22(15-12-20)37-18-21-13-10-19-6-3-4-9-25(19)31-21/h3-15H,16-18H2,1-2H3,(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...				Bioorg Med Chem 18: 5519-27 (2010) Article DOI: 10.1016/j.bmc.2010.06.047 BindingDB Entry DOI: 10.7270/Q26D5TZ0
					More data for this Ligand-Target Pair