Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 487.0 BDBM50001288

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50001288 (3-[{3-[2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(...) Show SMILES CN(C)CCSC(SCCC(O)=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C25H27ClN2O2S2/c1-28(2)13-15-32-25(31-14-12-24(29)30)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(26)17-23(19)27-22/h3-11,16-17,25H,12-15H2,1-2H3,(H,29,30)/b10-6+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranes				J Med Chem 35: 3832-44 (1992) BindingDB Entry DOI: 10.7270/Q2TQ625N
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