Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50045851
(CHEMBL3357954)Show SMILES CN(C)c1ccc(\C=C\C(=O)C2CCc3ccccc3C2=O)c(c1)[N+]([O-])=O Show InChI InChI=1S/C21H20N2O4/c1-22(2)16-10-7-15(19(13-16)23(26)27)9-12-20(24)18-11-8-14-5-3-4-6-17(14)21(18)25/h3-7,9-10,12-13,18H,8,11H2,1-2H3/b12-9+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Kebangsaan Malaysia
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 using arachidonic acid substrate assessed as PGE2 production ELISA method after 2 mins |
Bioorg Med Chem 22: 4151-61 (2014)
Article DOI: 10.1016/j.bmc.2014.05.052
BindingDB Entry DOI: 10.7270/Q2GX4D6F |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50045851
(CHEMBL3357954)Show SMILES CN(C)c1ccc(\C=C\C(=O)C2CCc3ccccc3C2=O)c(c1)[N+]([O-])=O Show InChI InChI=1S/C21H20N2O4/c1-22(2)16-10-7-15(19(13-16)23(26)27)9-12-20(24)18-11-8-14-5-3-4-6-17(14)21(18)25/h3-7,9-10,12-13,18H,8,11H2,1-2H3/b12-9+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Kebangsaan Malaysia
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant COX2 using arachidonic acid substrate assessed as PGE2 production ELISA method after 2 mins |
Bioorg Med Chem 22: 4151-61 (2014)
Article DOI: 10.1016/j.bmc.2014.05.052
BindingDB Entry DOI: 10.7270/Q2GX4D6F |
More data for this
Ligand-Target Pair | |
Lipoxygenase
(Glycine max) | BDBM50045851
(CHEMBL3357954)Show SMILES CN(C)c1ccc(\C=C\C(=O)C2CCc3ccccc3C2=O)c(c1)[N+]([O-])=O Show InChI InChI=1S/C21H20N2O4/c1-22(2)16-10-7-15(19(13-16)23(26)27)9-12-20(24)18-11-8-14-5-3-4-6-17(14)21(18)25/h3-7,9-10,12-13,18H,8,11H2,1-2H3/b12-9+ | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.57E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Kebangsaan Malaysia
Curated by ChEMBL
| Assay Description
Inhibition of soybean lipoxygenase after 5 mins by colorimetric assay |
Bioorg Med Chem 22: 4151-61 (2014)
Article DOI: 10.1016/j.bmc.2014.05.052
BindingDB Entry DOI: 10.7270/Q2GX4D6F |
More data for this
Ligand-Target Pair | |