Found 5 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM63381
((5Z)-3-[2-(5-amino-1,3,4-thiadiazol-2-yl)ethyl]-5-...)Show SMILES CN(C)c1ccc(\C=C2/SC(=O)N(CCc3nnc(N)s3)C2=O)cc1 Show InChI InChI=1S/C16H17N5O2S2/c1-20(2)11-5-3-10(4-6-11)9-12-14(22)21(16(23)24-12)8-7-13-18-19-15(17)25-13/h3-6,9H,7-8H2,1-2H3,(H2,17,19)/b12-9- | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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PC cid PC sid UniChem
| PCBioAssay
| n/a | n/a | 9.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2PC30VZ |
More data for this Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM63381
((5Z)-3-[2-(5-amino-1,3,4-thiadiazol-2-yl)ethyl]-5-...)Show SMILES CN(C)c1ccc(\C=C2/SC(=O)N(CCc3nnc(N)s3)C2=O)cc1 Show InChI InChI=1S/C16H17N5O2S2/c1-20(2)11-5-3-10(4-6-11)9-12-14(22)21(16(23)24-12)8-7-13-18-19-15(17)25-13/h3-6,9H,7-8H2,1-2H3,(H2,17,19)/b12-9- | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| PCBioAssay
| n/a | n/a | 9.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q28C9TQN |
More data for this Ligand-Target Pair | |
X-box-binding protein 1
(Homo sapiens (Human)) | BDBM63381
((5Z)-3-[2-(5-amino-1,3,4-thiadiazol-2-yl)ethyl]-5-...)Show SMILES CN(C)c1ccc(\C=C2/SC(=O)N(CCc3nnc(N)s3)C2=O)cc1 Show InChI InChI=1S/C16H17N5O2S2/c1-20(2)11-5-3-10(4-6-11)9-12-14(22)21(16(23)24-12)8-7-13-18-19-15(17)25-13/h3-6,9H,7-8H2,1-2H3,(H2,17,19)/b12-9- | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
| PCBioAssay
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q2NK3CGB |
More data for this Ligand-Target Pair | |
Insulin-degrading enzyme
(Homo sapiens (Human)) | BDBM63381
((5Z)-3-[2-(5-amino-1,3,4-thiadiazol-2-yl)ethyl]-5-...)Show SMILES CN(C)c1ccc(\C=C2/SC(=O)N(CCc3nnc(N)s3)C2=O)cc1 Show InChI InChI=1S/C16H17N5O2S2/c1-20(2)11-5-3-10(4-6-11)9-12-14(22)21(16(23)24-12)8-7-13-18-19-15(17)25-13/h3-6,9H,7-8H2,1-2H3,(H2,17,19)/b12-9- | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
| PCBioAssay
| n/a | n/a | >5.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2416VHJ |
More data for this Ligand-Target Pair | |
Heat shock factor protein 1
(Mus musculus) | BDBM63381
((5Z)-3-[2-(5-amino-1,3,4-thiadiazol-2-yl)ethyl]-5-...)Show SMILES CN(C)c1ccc(\C=C2/SC(=O)N(CCc3nnc(N)s3)C2=O)cc1 Show InChI InChI=1S/C16H17N5O2S2/c1-20(2)11-5-3-10(4-6-11)9-12-14(22)21(16(23)24-12)8-7-13-18-19-15(17)25-13/h3-6,9H,7-8H2,1-2H3,(H2,17,19)/b12-9- | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| PCBioAssay
| n/a | n/a | n/a | n/a | 6.52E+3 | n/a | n/a | n/a | n/a |
Broad Institute
Curated by PubChem BioAssay
| Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2MW2FKX |
More data for this Ligand-Target Pair | |