Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human)) | BDBM354736
(Preparation of 5-(3-(1H-indol-5-yl)-1H-pyrrolo[2,3...)Show SMILES CN(C)c1ccc(cn1)-c1cnc2[nH]cc(-c3ccc4[nH]ccc4c3)c2c1 Show InChI InChI=1S/C22H19N5/c1-27(2)21-6-4-16(11-24-21)17-10-18-19(13-26-22(18)25-12-17)14-3-5-20-15(9-14)7-8-23-20/h3-13,23H,1-2H3,(H,25,26) | PDB
NCI pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Rochester; Board of Regents of the University of Nebraska
US Patent
| Assay Description
200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ... |
US Patent US10485800 (2019)
BindingDB Entry DOI: 10.7270/Q22B91DW |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human)) | BDBM354736
(Preparation of 5-(3-(1H-indol-5-yl)-1H-pyrrolo[2,3...)Show SMILES CN(C)c1ccc(cn1)-c1cnc2[nH]cc(-c3ccc4[nH]ccc4c3)c2c1 Show InChI InChI=1S/C22H19N5/c1-27(2)21-6-4-16(11-24-21)17-10-18-19(13-26-22(18)25-12-17)14-3-5-20-15(9-14)7-8-23-20/h3-13,23H,1-2H3,(H,25,26) | PDB
NCI pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Rochester
US Patent
| Assay Description
200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ... |
US Patent US9814704 (2017)
BindingDB Entry DOI: 10.7270/Q27H1MRN |
More data for this
Ligand-Target Pair | |