Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Opioid growth factor receptor-like protein 1
(Homo sapiens (Human)) | BDBM133973
(US8846929, 2)Show SMILES CN(C)c1nc2ccccc2n(C2CCN(CC2)C2CCCCCCC2)c1=O Show InChI InChI=1S/C23H34N4O/c1-25(2)22-23(28)27(21-13-9-8-12-20(21)24-22)19-14-16-26(17-15-19)18-10-6-4-3-5-7-11-18/h8-9,12-13,18-19H,3-7,10-11,14-17H2,1-2H3 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| 67.2 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma L.P.; Shionogi & Co., Ltd.
US Patent
| Assay Description
Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin... |
US Patent US8846929 (2014)
BindingDB Entry DOI: 10.7270/Q2G44P04 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM133973
(US8846929, 2)Show SMILES CN(C)c1nc2ccccc2n(C2CCN(CC2)C2CCCCCCC2)c1=O Show InChI InChI=1S/C23H34N4O/c1-25(2)22-23(28)27(21-13-9-8-12-20(21)24-22)19-14-16-26(17-15-19)18-10-6-4-3-5-7-11-18/h8-9,12-13,18-19H,3-7,10-11,14-17H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 257 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma L.P.; Shionogi & Co., Ltd.
US Patent
| Assay Description
Radioligand dose displacement assays used 0.4-0.8nM [3H]-U69,593 (NEN; 40 Ci/mmole) with 10-20 ug membrane protein (recombinant kappa opioid receptor... |
US Patent US8846929 (2014)
BindingDB Entry DOI: 10.7270/Q2G44P04 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM133973
(US8846929, 2)Show SMILES CN(C)c1nc2ccccc2n(C2CCN(CC2)C2CCCCCCC2)c1=O Show InChI InChI=1S/C23H34N4O/c1-25(2)22-23(28)27(21-13-9-8-12-20(21)24-22)19-14-16-26(17-15-19)18-10-6-4-3-5-7-11-18/h8-9,12-13,18-19H,3-7,10-11,14-17H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 2.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma L.P.; Shionogi & Co., Ltd.
US Patent
| Assay Description
Radioligand dose-displacement binding assays for u-opioid receptors used 0.2nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20mg membrane protein/w... |
US Patent US8846929 (2014)
BindingDB Entry DOI: 10.7270/Q2G44P04 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM133973
(US8846929, 2)Show SMILES CN(C)c1nc2ccccc2n(C2CCN(CC2)C2CCCCCCC2)c1=O Show InChI InChI=1S/C23H34N4O/c1-25(2)22-23(28)27(21-13-9-8-12-20(21)24-22)19-14-16-26(17-15-19)18-10-6-4-3-5-7-11-18/h8-9,12-13,18-19H,3-7,10-11,14-17H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 2.81E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma L.P.; Shionogi & Co., Ltd.
US Patent
| Assay Description
Radioligand dose-displacement assays used 0.2nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20ug membrane protein (recombinant delta opioid recepto... |
US Patent US8846929 (2014)
BindingDB Entry DOI: 10.7270/Q2G44P04 |
More data for this
Ligand-Target Pair | |