Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 333.1 BDBM50003721

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50003721 (CHEMBL3235287) Show SMILES CN(C)c1ncnc2OCC(=Nc12)c1ccc(Br)cc1 |c:10| Show InChI InChI=1S/C14H13BrN4O/c1-19(2)13-12-14(17-8-16-13)20-7-11(18-12)9-3-5-10(15)6-4-9/h3-6,8H,7H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPA				J Med Chem 57: 3464-83 (2014) Article DOI: 10.1021/jm500135c BindingDB Entry DOI: 10.7270/Q23X886W
					More data for this Ligand-Target Pair