Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 489.6 BDBM50089051

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50089051 (CHEMBL17911 | Naphthalene-1-sulfonic acid {4-[(4-a...) Show SMILES CN(C[C@H]1CC[C@H](CNc2nc(N)c3ccccc3n2)CC1)S(=O)(=O)c1cccc2ccccc12 |wU:6.6,wD:3.2,(11.05,-6.14,;11.27,-4.67,;9.78,-5.07,;8.45,-4.3,;8.47,-2.76,;7.14,-1.98,;5.79,-2.75,;4.46,-1.99,;3.13,-2.75,;1.78,-1.98,;1.78,-.43,;.43,.34,;.43,1.88,;-.9,-.44,;-2.24,.33,;-3.58,-.44,;-3.58,-1.99,;-2.24,-2.78,;-.9,-1.99,;.45,-2.76,;5.79,-4.29,;7.12,-5.06,;12.6,-5.44,;12.58,-3.9,;12.58,-6.98,;14.13,-5.44,;14.47,-3.94,;15.95,-3.48,;17.08,-4.53,;16.73,-6.02,;17.86,-7.07,;17.52,-8.57,;16.05,-9.03,;14.93,-7.98,;15.26,-6.48,)| Show InChI InChI=1S/C27H31N5O2S/c1-32(35(33,34)25-12-6-8-21-7-2-3-9-22(21)25)18-20-15-13-19(14-16-20)17-29-27-30-24-11-5-4-10-23(24)26(28)31-27/h2-12,19-20H,13-18H2,1H3,(H3,28,29,30,31)/t19-,20-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Antagonistic activity against neuropeptide Y receptor type 5 subtype stably expressed in LM(tk-)cells				Bioorg Med Chem Lett 10: 1175-9 (2000) BindingDB Entry DOI: 10.7270/Q2KH0MJP
					More data for this Ligand-Target Pair