Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM34027
(phenylpropanoic acid derivative, 44)Show SMILES CN(C\C=C\c1ccc(C[C@@H](C(O)=O)n2cccc2)cc1)c1ccccc1 |r| Show InChI InChI=1S/C23H24N2O2/c1-24(21-9-3-2-4-10-21)15-7-8-19-11-13-20(14-12-19)18-22(23(26)27)25-16-5-6-17-25/h2-14,16-17,22H,15,18H2,1H3,(H,26,27)/b8-7+/t22-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | 3.70E+3 | n/a | n/a | 7.4 | 23 |
Pfizer
| Assay Description
Human 6His-PPAR gamma ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysin... |
Bioorg Med Chem 16: 4883-907 (2008)
Article DOI: 10.1016/j.bmc.2008.03.043
BindingDB Entry DOI: 10.7270/Q2SN0797 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM34027
(phenylpropanoic acid derivative, 44)Show SMILES CN(C\C=C\c1ccc(C[C@@H](C(O)=O)n2cccc2)cc1)c1ccccc1 |r| Show InChI InChI=1S/C23H24N2O2/c1-24(21-9-3-2-4-10-21)15-7-8-19-11-13-20(14-12-19)18-22(23(26)27)25-16-5-6-17-25/h2-14,16-17,22H,15,18H2,1H3,(H,26,27)/b8-7+/t22-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | 25 |
Novartis
| Assay Description
Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al... |
J Med Chem 52: 6193-6 (2009)
Article DOI: 10.1021/jm901108b
BindingDB Entry DOI: 10.7270/Q25X278Q |
More data for this
Ligand-Target Pair | |