Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 334.4 BDBM50139415

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lanosterol synthase (Homo sapiens (Human))	BDBM50139415 (CHEMBL3764281) Show SMILES CN(C\C=C\c1ccccc1)Cc1ccc(cc1)C1CCCN(C)C1 Show InChI InChI=1S/C23H30N2/c1-24(16-6-10-20-8-4-3-5-9-20)18-21-12-14-22(15-13-21)23-11-7-17-25(2)19-23/h3-6,8-10,12-15,23H,7,11,16-19H2,1-2H3/b10-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Curated by ChEMBL					Assay Description Inhibition of human OSC expressed in recombinant Saccharomyces cerevisiae SMY8 using [14C]-(3S)-2,3-oxidosqualene as substrate				Eur J Med Chem 109: 13-22 (2016) Article DOI: 10.1016/j.ejmech.2015.12.025 BindingDB Entry DOI: 10.7270/Q2T43VZG
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