Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251623
(4-((3-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)...)Show SMILES CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)C1CCN(Cc2ccc(cc2)C(O)=O)C1 Show InChI InChI=1S/C27H29N3O4/c1-29(23-15-16-30(18-23)17-20-7-9-21(10-8-20)27(32)33)19-26(31)28-22-11-13-25(14-12-22)34-24-5-3-2-4-6-24/h2-14,23H,15-19H2,1H3,(H,28,31)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251623
(4-((3-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)...)Show SMILES CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)C1CCN(Cc2ccc(cc2)C(O)=O)C1 Show InChI InChI=1S/C27H29N3O4/c1-29(23-15-16-30(18-23)17-20-7-9-21(10-8-20)27(32)33)19-26(31)28-22-11-13-25(14-12-22)34-24-5-3-2-4-6-24/h2-14,23H,15-19H2,1H3,(H,28,31)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251623
(4-((3-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)...)Show SMILES CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)C1CCN(Cc2ccc(cc2)C(O)=O)C1 Show InChI InChI=1S/C27H29N3O4/c1-29(23-15-16-30(18-23)17-20-7-9-21(10-8-20)27(32)33)19-26(31)28-22-11-13-25(14-12-22)34-24-5-3-2-4-6-24/h2-14,23H,15-19H2,1H3,(H,28,31)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251623
(4-((3-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)...)Show SMILES CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)C1CCN(Cc2ccc(cc2)C(O)=O)C1 Show InChI InChI=1S/C27H29N3O4/c1-29(23-15-16-30(18-23)17-20-7-9-21(10-8-20)27(32)33)19-26(31)28-22-11-13-25(14-12-22)34-24-5-3-2-4-6-24/h2-14,23H,15-19H2,1H3,(H,28,31)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |