Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251555
(4-((methyl((1-(2-oxo-2-(4-phenoxyphenylamino)ethyl...)Show SMILES CN(CC1CCCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H33N3O4/c1-31(19-22-10-12-23(13-11-22)29(34)35)20-25-7-5-6-18-32(25)21-28(33)30-24-14-16-27(17-15-24)36-26-8-3-2-4-9-26/h2-4,8-17,25H,5-7,18-21H2,1H3,(H,30,33)(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251555
(4-((methyl((1-(2-oxo-2-(4-phenoxyphenylamino)ethyl...)Show SMILES CN(CC1CCCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H33N3O4/c1-31(19-22-10-12-23(13-11-22)29(34)35)20-25-7-5-6-18-32(25)21-28(33)30-24-14-16-27(17-15-24)36-26-8-3-2-4-9-26/h2-4,8-17,25H,5-7,18-21H2,1H3,(H,30,33)(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251555
(4-((methyl((1-(2-oxo-2-(4-phenoxyphenylamino)ethyl...)Show SMILES CN(CC1CCCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H33N3O4/c1-31(19-22-10-12-23(13-11-22)29(34)35)20-25-7-5-6-18-32(25)21-28(33)30-24-14-16-27(17-15-24)36-26-8-3-2-4-9-26/h2-4,8-17,25H,5-7,18-21H2,1H3,(H,30,33)(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251555
(4-((methyl((1-(2-oxo-2-(4-phenoxyphenylamino)ethyl...)Show SMILES CN(CC1CCCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H33N3O4/c1-31(19-22-10-12-23(13-11-22)29(34)35)20-25-7-5-6-18-32(25)21-28(33)30-24-14-16-27(17-15-24)36-26-8-3-2-4-9-26/h2-4,8-17,25H,5-7,18-21H2,1H3,(H,30,33)(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |