Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50083131
(1-Methyl-3-phenyl-1-{1-[3-(5-[1,2,4]triazol-4-yl-1...)Show SMILES CN(CC1CCN(CCCc2c[nH]c3ccc(cc23)-n2cnnc2)CC1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C27H33N7O/c1-32(27(35)31-23-7-3-2-4-8-23)18-21-11-14-33(15-12-21)13-5-6-22-17-28-26-10-9-24(16-25(22)26)34-19-29-30-20-34/h2-4,7-10,16-17,19-21,28H,5-6,11-15,18H2,1H3,(H,31,35) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cells |
J Med Chem 42: 4981-5001 (2000)
BindingDB Entry DOI: 10.7270/Q20P0Z77 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50083131
(1-Methyl-3-phenyl-1-{1-[3-(5-[1,2,4]triazol-4-yl-1...)Show SMILES CN(CC1CCN(CCCc2c[nH]c3ccc(cc23)-n2cnnc2)CC1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C27H33N7O/c1-32(27(35)31-23-7-3-2-4-8-23)18-21-11-14-33(15-12-21)13-5-6-22-17-28-26-10-9-24(16-25(22)26)34-19-29-30-20-34/h2-4,7-10,16-17,19-21,28H,5-6,11-15,18H2,1H3,(H,31,35) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]-5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cells |
J Med Chem 42: 4981-5001 (2000)
BindingDB Entry DOI: 10.7270/Q20P0Z77 |
More data for this Ligand-Target Pair | |