Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lanosterol synthase
(Homo sapiens (Human)) | BDBM50128053
(Allyl-[6-(1,3-dimethyl-1H-indazol-6-yloxy)-hexyl]-...)Show InChI InChI=1S/C19H29N3O/c1-5-12-21(3)13-8-6-7-9-14-23-17-10-11-18-16(2)20-22(4)19(18)15-17/h5,10-11,15H,1,6-9,12-14H2,2-4H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Albert-Ludwigs-Universität
Curated by ChEMBL
| Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomes |
J Med Chem 46: 2083-92 (2003)
Article DOI: 10.1021/jm0211218 BindingDB Entry DOI: 10.7270/Q2VM4BM9 |
More data for this Ligand-Target Pair | |
Squalene--hopene cyclase
(Alicyclobacillus acidocaldarius) | BDBM50128053
(Allyl-[6-(1,3-dimethyl-1H-indazol-6-yloxy)-hexyl]-...)Show InChI InChI=1S/C19H29N3O/c1-5-12-21(3)13-8-6-7-9-14-23-17-10-11-18-16(2)20-22(4)19(18)15-17/h5,10-11,15H,1,6-9,12-14H2,2-4H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 332 | n/a | n/a | n/a | n/a | n/a | n/a |
Albert-Ludwigs-Universität
Curated by ChEMBL
| Assay Description Inhibitory activity against squalene hopene cyclase from Alicyclobacillus acidocaldarius |
J Med Chem 46: 2083-92 (2003)
Article DOI: 10.1021/jm0211218 BindingDB Entry DOI: 10.7270/Q2VM4BM9 |
More data for this Ligand-Target Pair | |