Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50375112
(CHEMBL257031)Show SMILES CN(CCCCn1c2c(Cl)cccc2n(CC(=O)c2ccc(Cl)cc2)c1=N)C(=O)Cc1ccccc1 Show InChI InChI=1S/C28H28Cl2N4O2/c1-32(26(36)18-20-8-3-2-4-9-20)16-5-6-17-33-27-23(30)10-7-11-24(27)34(28(33)31)19-25(35)21-12-14-22(29)15-13-21/h2-4,7-15,31H,5-6,16-19H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center
Curated by ChEMBL
| Assay Description Antagonist activity at human CXCR3 expressed in CHO cell membrane assessed as inhibition of calcium flux by FLIPR |
Bioorg Med Chem Lett 18: 2414-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.049 BindingDB Entry DOI: 10.7270/Q2BP03NC |
More data for this Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50375112
(CHEMBL257031)Show SMILES CN(CCCCn1c2c(Cl)cccc2n(CC(=O)c2ccc(Cl)cc2)c1=N)C(=O)Cc1ccccc1 Show InChI InChI=1S/C28H28Cl2N4O2/c1-32(26(36)18-20-8-3-2-4-9-20)16-5-6-17-33-27-23(30)10-7-11-24(27)34(28(33)31)19-25(35)21-12-14-22(29)15-13-21/h2-4,7-15,31H,5-6,16-19H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center
Curated by ChEMBL
| Assay Description Displacement of [125I]-CXCL10 from human CXCR3 expressed in CHO cell membrane |
Bioorg Med Chem Lett 18: 2414-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.049 BindingDB Entry DOI: 10.7270/Q2BP03NC |
More data for this Ligand-Target Pair | |