Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50375118
(CHEMBL404517)Show SMILES CN(CCCn1c2c(Cl)cccc2n(CC(=O)c2ccc(Cl)cc2)c1=N)C(=O)C(C)(C)C Show InChI InChI=1S/C24H28Cl2N4O2/c1-24(2,3)22(32)28(4)13-6-14-29-21-18(26)7-5-8-19(21)30(23(29)27)15-20(31)16-9-11-17(25)12-10-16/h5,7-12,27H,6,13-15H2,1-4H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center
Curated by ChEMBL
| Assay Description Antagonist activity at human CXCR3 expressed in CHO cell membrane assessed as inhibition of calcium flux by FLIPR |
Bioorg Med Chem Lett 18: 2414-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.049 BindingDB Entry DOI: 10.7270/Q2BP03NC |
More data for this Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50375118
(CHEMBL404517)Show SMILES CN(CCCn1c2c(Cl)cccc2n(CC(=O)c2ccc(Cl)cc2)c1=N)C(=O)C(C)(C)C Show InChI InChI=1S/C24H28Cl2N4O2/c1-24(2,3)22(32)28(4)13-6-14-29-21-18(26)7-5-8-19(21)30(23(29)27)15-20(31)16-9-11-17(25)12-10-16/h5,7-12,27H,6,13-15H2,1-4H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center
Curated by ChEMBL
| Assay Description Displacement of [125I]-CXCL10 from human CXCR3 expressed in CHO cell membrane |
Bioorg Med Chem Lett 18: 2414-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.049 BindingDB Entry DOI: 10.7270/Q2BP03NC |
More data for this Ligand-Target Pair | |