Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Amyloid-beta precursor protein [1-42]
(Homo sapiens (Human)) | BDBM481160
(US10906900, Reference 28)Show InChI InChI=1S/C18H16FN3/c1-22(12-10-19)17-8-5-14(6-9-17)4-7-16-13-15-3-2-11-20-18(15)21-16/h2-3,5-6,8-9,11,13H,10,12H2,1H3,(H,20,21) | MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
US Patent
| Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p... |
US Patent US10906900 (2021)
BindingDB Entry DOI: 10.7270/Q2BC42NC |
More data for this Ligand-Target Pair | |
Alpha-synuclein
(Homo sapiens (Human)) | BDBM481160
(US10906900, Reference 28)Show InChI InChI=1S/C18H16FN3/c1-22(12-10-19)17-8-5-14(6-9-17)4-7-16-13-15-3-2-11-20-18(15)21-16/h2-3,5-6,8-9,11,13H,10,12H2,1H3,(H,20,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
US Patent
| Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p... |
US Patent US10906900 (2021)
BindingDB Entry DOI: 10.7270/Q2BC42NC |
More data for this Ligand-Target Pair | |
Isoform Tau-F of Microtubule-associated protein tau
(Homo sapiens (Human)) | BDBM481160
(US10906900, Reference 28)Show InChI InChI=1S/C18H16FN3/c1-22(12-10-19)17-8-5-14(6-9-17)4-7-16-13-15-3-2-11-20-18(15)21-16/h2-3,5-6,8-9,11,13H,10,12H2,1H3,(H,20,21) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | 0.970 | n/a | n/a | n/a | n/a | n/a |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
US Patent
| Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p... |
US Patent US10906900 (2021)
BindingDB Entry DOI: 10.7270/Q2BC42NC |
More data for this Ligand-Target Pair | |
Alpha-synuclein
(Homo sapiens (Human)) | BDBM481160
(US10906900, Reference 28)Show InChI InChI=1S/C18H16FN3/c1-22(12-10-19)17-8-5-14(6-9-17)4-7-16-13-15-3-2-11-20-18(15)21-16/h2-3,5-6,8-9,11,13H,10,12H2,1H3,(H,20,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
US Patent
| Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p... |
US Patent US10906900 (2021)
BindingDB Entry DOI: 10.7270/Q2BC42NC |
More data for this Ligand-Target Pair | |