Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50375129
(CHEMBL270462)Show SMILES CN(CCn1c2ccccc2n(CC(=O)c2ccc(Cl)cc2)c1=N)C(=O)C1CCCCC1 Show InChI InChI=1S/C25H29ClN4O2/c1-28(24(32)19-7-3-2-4-8-19)15-16-29-21-9-5-6-10-22(21)30(25(29)27)17-23(31)18-11-13-20(26)14-12-18/h5-6,9-14,19,27H,2-4,7-8,15-17H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center
Curated by ChEMBL
| Assay Description Displacement of [125I]-CXCL10 from human CXCR3 expressed in CHO cell membrane |
Bioorg Med Chem Lett 18: 2414-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.049 BindingDB Entry DOI: 10.7270/Q2BP03NC |
More data for this Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50375129
(CHEMBL270462)Show SMILES CN(CCn1c2ccccc2n(CC(=O)c2ccc(Cl)cc2)c1=N)C(=O)C1CCCCC1 Show InChI InChI=1S/C25H29ClN4O2/c1-28(24(32)19-7-3-2-4-8-19)15-16-29-21-9-5-6-10-22(21)30(25(29)27)17-23(31)18-11-13-20(26)14-12-18/h5-6,9-14,19,27H,2-4,7-8,15-17H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center
Curated by ChEMBL
| Assay Description Antagonist activity at human CXCR3 expressed in CHO cell membrane assessed as inhibition of calcium flux by FLIPR |
Bioorg Med Chem Lett 18: 2414-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.049 BindingDB Entry DOI: 10.7270/Q2BP03NC |
More data for this Ligand-Target Pair | |