Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 368.9 BDBM50139417

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lanosterol synthase (Homo sapiens (Human))	BDBM50139417 (CHEMBL3765660) Show SMILES CN(Cc1ccc(Cl)cc1)C1CCc2cc(ccc12)C1CCCN(C)C1 Show InChI InChI=1S/C23H29ClN2/c1-25-13-3-4-20(16-25)18-7-11-22-19(14-18)8-12-23(22)26(2)15-17-5-9-21(24)10-6-17/h5-7,9-11,14,20,23H,3-4,8,12-13,15-16H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Curated by ChEMBL					Assay Description Inhibition of human OSC expressed in recombinant Saccharomyces cerevisiae SMY8 using [14C]-(3S)-2,3-oxidosqualene as substrate				Eur J Med Chem 109: 13-22 (2016) Article DOI: 10.1016/j.ejmech.2015.12.025 BindingDB Entry DOI: 10.7270/Q2T43VZG
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