Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 340.8 BDBM50139397

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lanosterol synthase (Homo sapiens (Human))	BDBM50139397 (CHEMBL3765017) Show SMILES CN(Cc1ccc(Cl)cc1)Cc1ccc(cc1)C1=CCCN(C)C1 |t:19| Show InChI InChI=1S/C21H25ClN2/c1-23-13-3-4-20(16-23)19-9-5-17(6-10-19)14-24(2)15-18-7-11-21(22)12-8-18/h4-12H,3,13-16H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Curated by ChEMBL					Assay Description Inhibition of human OSC expressed in recombinant Saccharomyces cerevisiae SMY8 using [14C]-(3S)-2,3-oxidosqualene as substrate				Eur J Med Chem 109: 13-22 (2016) Article DOI: 10.1016/j.ejmech.2015.12.025 BindingDB Entry DOI: 10.7270/Q2T43VZG
					More data for this Ligand-Target Pair