Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251668
(4-((methyl(4-(4-(4-(oxazol-2-yl)phenoxy)phenylamin...)Show SMILES CN(Cc1ccc(cc1)C(O)=O)C1CCC(CC1)Nc1ccc(Oc2ccc(cc2)-c2ncco2)cc1 |(36.8,-1.72,;36.79,-.18,;38.13,.59,;39.48,-.18,;39.49,-1.72,;40.83,-2.47,;42.15,-1.69,;42.13,-.15,;40.79,.6,;43.5,-2.45,;43.51,-3.99,;44.81,-1.67,;35.45,.58,;34.14,-.2,;32.8,.56,;32.79,2.1,;34.11,2.88,;35.45,2.13,;31.44,2.88,;30.1,2.1,;30.11,.56,;28.79,-.22,;27.43,.56,;26.07,-.2,;24.74,.6,;23.4,-.16,;22.07,.62,;22.1,2.17,;23.44,2.92,;24.76,2.15,;20.78,2.96,;19.33,2.42,;18.38,3.62,;19.24,4.91,;20.71,4.49,;27.43,2.1,;28.76,2.88,)| Show InChI InChI=1S/C30H31N3O4/c1-33(20-21-2-4-23(5-3-21)30(34)35)26-12-8-24(9-13-26)32-25-10-16-28(17-11-25)37-27-14-6-22(7-15-27)29-31-18-19-36-29/h2-7,10-11,14-19,24,26,32H,8-9,12-13,20H2,1H3,(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) |
Bioorg Med Chem Lett 18: 3895-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.041
BindingDB Entry DOI: 10.7270/Q2GQ6XK8 |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251668
(4-((methyl(4-(4-(4-(oxazol-2-yl)phenoxy)phenylamin...)Show SMILES CN(Cc1ccc(cc1)C(O)=O)C1CCC(CC1)Nc1ccc(Oc2ccc(cc2)-c2ncco2)cc1 |(36.8,-1.72,;36.79,-.18,;38.13,.59,;39.48,-.18,;39.49,-1.72,;40.83,-2.47,;42.15,-1.69,;42.13,-.15,;40.79,.6,;43.5,-2.45,;43.51,-3.99,;44.81,-1.67,;35.45,.58,;34.14,-.2,;32.8,.56,;32.79,2.1,;34.11,2.88,;35.45,2.13,;31.44,2.88,;30.1,2.1,;30.11,.56,;28.79,-.22,;27.43,.56,;26.07,-.2,;24.74,.6,;23.4,-.16,;22.07,.62,;22.1,2.17,;23.44,2.92,;24.76,2.15,;20.78,2.96,;19.33,2.42,;18.38,3.62,;19.24,4.91,;20.71,4.49,;27.43,2.1,;28.76,2.88,)| Show InChI InChI=1S/C30H31N3O4/c1-33(20-21-2-4-23(5-3-21)30(34)35)26-12-8-24(9-13-26)32-25-10-16-28(17-11-25)37-27-14-6-22(7-15-27)29-31-18-19-36-29/h2-7,10-11,14-19,24,26,32H,8-9,12-13,20H2,1H3,(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase in human whole blood |
Bioorg Med Chem Lett 18: 3895-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.041
BindingDB Entry DOI: 10.7270/Q2GQ6XK8 |
More data for this
Ligand-Target Pair | |