Found 6 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM323597
((E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl...)Show SMILES CN(Cc1ccccc1OCCC\C(C)=C\C(O)=O)C(=O)c1ccc(cc1)-c1ccco1 Show InChI InChI=1S/C26H27NO5/c1-19(17-25(28)29)7-5-15-32-24-9-4-3-8-22(24)18-27(2)26(30)21-13-11-20(12-14-21)23-10-6-16-31-23/h3-4,6,8-14,16-17H,5,7,15,18H2,1-2H3,(H,28,29)/b19-17+ | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 694 | n/a | n/a | n/a | n/a |
Mitobridge, Inc.; Salk Institute for Biological Studies
US Patent
| Assay Description
Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif... |
US Patent US10188627 (2019)
BindingDB Entry DOI: 10.7270/Q2HX1FR6 |
More data for this
Ligand-Target Pair | |
PPAR delta protein
(Rattus norvegicus (Rat)) | BDBM323597
((E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl...)Show SMILES CN(Cc1ccccc1OCCC\C(C)=C\C(O)=O)C(=O)c1ccc(cc1)-c1ccco1 Show InChI InChI=1S/C26H27NO5/c1-19(17-25(28)29)7-5-15-32-24-9-4-3-8-22(24)18-27(2)26(30)21-13-11-20(12-14-21)23-10-6-16-31-23/h3-4,6,8-14,16-17H,5,7,15,18H2,1-2H3,(H,28,29)/b19-17+ | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 694 | n/a | n/a | n/a | n/a |
Mitobridge, Inc.; Salk Institute for Biological Studies
US Patent
| Assay Description
Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif... |
US Patent US10188627 (2019)
BindingDB Entry DOI: 10.7270/Q2HX1FR6 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM323597
((E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl...)Show SMILES CN(Cc1ccccc1OCCC\C(C)=C\C(O)=O)C(=O)c1ccc(cc1)-c1ccco1 Show InChI InChI=1S/C26H27NO5/c1-19(17-25(28)29)7-5-15-32-24-9-4-3-8-22(24)18-27(2)26(30)21-13-11-20(12-14-21)23-10-6-16-31-23/h3-4,6,8-14,16-17H,5,7,15,18H2,1-2H3,(H,28,29)/b19-17+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Mitobridge, Inc.
Curated by ChEMBL
| Assay Description
Activation of human PPARgamma LBD expressed in CHO-K1 cells by beta galactosidase enzyme fragment complement based fluorescence assay |
Bioorg Med Chem Lett 27: 5230-5234 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.037
BindingDB Entry DOI: 10.7270/Q21V5HJT |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM323597
((E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl...)Show SMILES CN(Cc1ccccc1OCCC\C(C)=C\C(O)=O)C(=O)c1ccc(cc1)-c1ccco1 Show InChI InChI=1S/C26H27NO5/c1-19(17-25(28)29)7-5-15-32-24-9-4-3-8-22(24)18-27(2)26(30)21-13-11-20(12-14-21)23-10-6-16-31-23/h3-4,6,8-14,16-17H,5,7,15,18H2,1-2H3,(H,28,29)/b19-17+ | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Mitobridge, Inc.
Curated by ChEMBL
| Assay Description
Activation of human PPARalpha LBD expressed in CHO-K1 cells by beta galactosidase enzyme fragment complement based fluorescence assay |
Bioorg Med Chem Lett 27: 5230-5234 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.037
BindingDB Entry DOI: 10.7270/Q21V5HJT |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM323597
((E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl...)Show SMILES CN(Cc1ccccc1OCCC\C(C)=C\C(O)=O)C(=O)c1ccc(cc1)-c1ccco1 Show InChI InChI=1S/C26H27NO5/c1-19(17-25(28)29)7-5-15-32-24-9-4-3-8-22(24)18-27(2)26(30)21-13-11-20(12-14-21)23-10-6-16-31-23/h3-4,6,8-14,16-17H,5,7,15,18H2,1-2H3,(H,28,29)/b19-17+ | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 690 | n/a | n/a | n/a | n/a |
Mitobridge, Inc.
Curated by ChEMBL
| Assay Description
Activation of human PPARdelta LBD expressed in CHO-K1 cells by beta galactosidase enzyme fragment complement based fluorescence assay |
Bioorg Med Chem Lett 27: 5230-5234 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.037
BindingDB Entry DOI: 10.7270/Q21V5HJT |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM323597
((E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl...)Show SMILES CN(Cc1ccccc1OCCC\C(C)=C\C(O)=O)C(=O)c1ccc(cc1)-c1ccco1 Show InChI InChI=1S/C26H27NO5/c1-19(17-25(28)29)7-5-15-32-24-9-4-3-8-22(24)18-27(2)26(30)21-13-11-20(12-14-21)23-10-6-16-31-23/h3-4,6,8-14,16-17H,5,7,15,18H2,1-2H3,(H,28,29)/b19-17+ | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Mitobridge, Inc.
Curated by ChEMBL
| Assay Description
Transactivation of yeast GAL4 DNA binding domain-fused PPARdelta LBD (unknown origin) expressed in CV-1 cells after 24 hrs by luciferase reporter gen... |
Bioorg Med Chem Lett 27: 5230-5234 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.037
BindingDB Entry DOI: 10.7270/Q21V5HJT |
More data for this
Ligand-Target Pair | |