Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 408.4 BDBM475602

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage metalloelastase (Homo sapiens (Human))	BDBM475602 (US10851089, Compound FC-33) Show SMILES CN(Cc1ccnc(C)c1)c1ccc(Sc2ccoc2C2NC(=O)NC2=O)cc1 Show InChI InChI=1S/C21H20N4O3S/c1-13-11-14(7-9-22-13)12-25(2)15-3-5-16(6-4-15)29-17-8-10-28-19(17)18-20(26)24-21(27)23-18/h3-11,18H,12H2,1-2H3,(H2,23,24,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Foresee Pharmaceuticals Co., Ltd. US Patent					Assay Description The inhibitory effect of compounds on the rate of cleaving fluorogenic MMP substrate (Enzo, BML-P128) by recombinant human MMP-12 catalytic domain (E...				US Patent US10851089 (2020) BindingDB Entry DOI: 10.7270/Q21J9DV1
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