Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 432.4 BDBM50580367

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50580367 (CHEMBL5076771) Show SMILES CN(Cc1sc(nc1C)-c1ccc(cc1)C(F)(F)F)c1ccc(\C=C\C(O)=O)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	947	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human PPARalpha transfected in COS-7 cells assessed luciferase activity measured after 24 hrs by cell based luciferase transactiv...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00560 BindingDB Entry DOI: 10.7270/Q2Q81HXK
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50580367 (CHEMBL5076771) Show SMILES CN(Cc1sc(nc1C)-c1ccc(cc1)C(F)(F)F)c1ccc(\C=C\C(O)=O)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.47E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human PPARgamma transfected in COS-7 cells assessed luciferase activity measured after 24 hrs by cell based luciferase transactiv...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00560 BindingDB Entry DOI: 10.7270/Q2Q81HXK
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50580367 (CHEMBL5076771) Show SMILES CN(Cc1sc(nc1C)-c1ccc(cc1)C(F)(F)F)c1ccc(\C=C\C(O)=O)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	199	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human PPARdelta transfected in COS-7 cells assessed luciferase activity measured after 24 hrs by cell based luciferase transactiv...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00560 BindingDB Entry DOI: 10.7270/Q2Q81HXK
					More data for this Ligand-Target Pair