Found 12 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50542862
(CHEMBL4642345)Show SMILES CN[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C28H49N11O5/c1-16(2)14-22(39-24(42)19(34-3)6-4-12-35-27(30)31)26(44)37-20(7-5-13-36-28(32)33)25(43)38-21(23(29)41)15-17-8-10-18(40)11-9-17/h8-11,16,19-22,34,40H,4-7,12-15H2,1-3H3,(H2,29,41)(H,37,44)(H,38,43)(H,39,42)(H4,30,31,35)(H4,32,33,36)/t19-,20-,21-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description
Displacement of [3H]UR-KK200 from human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ measured after 90 mins by scintillation counting ... |
J Med Chem 63: 8198-8215 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00426
BindingDB Entry DOI: 10.7270/Q22R3W7V |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50542862
(CHEMBL4642345)Show SMILES CN[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C28H49N11O5/c1-16(2)14-22(39-24(42)19(34-3)6-4-12-35-27(30)31)26(44)37-20(7-5-13-36-28(32)33)25(43)38-21(23(29)41)15-17-8-10-18(40)11-9-17/h8-11,16,19-22,34,40H,4-7,12-15H2,1-3H3,(H2,29,41)(H,37,44)(H,38,43)(H,39,42)(H4,30,31,35)(H4,32,33,36)/t19-,20-,21-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description
Displacement of [3H]UR-KK200 from human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ measured after 90 mins by scintillation counting ... |
J Med Chem 63: 8198-8215 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00426
BindingDB Entry DOI: 10.7270/Q22R3W7V |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50542862
(CHEMBL4642345)Show SMILES CN[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C28H49N11O5/c1-16(2)14-22(39-24(42)19(34-3)6-4-12-35-27(30)31)26(44)37-20(7-5-13-36-28(32)33)25(43)38-21(23(29)41)15-17-8-10-18(40)11-9-17/h8-11,16,19-22,34,40H,4-7,12-15H2,1-3H3,(H2,29,41)(H,37,44)(H,38,43)(H,39,42)(H4,30,31,35)(H4,32,33,36)/t19-,20-,21-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description
Displacement of [3H]propionyl-pNPY from human Y2 receptor expressed in CHO cells measured after 2 hrs by microbeta liquid scintillation counting anal... |
J Med Chem 63: 8198-8215 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00426
BindingDB Entry DOI: 10.7270/Q22R3W7V |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50542862
(CHEMBL4642345)Show SMILES CN[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C28H49N11O5/c1-16(2)14-22(39-24(42)19(34-3)6-4-12-35-27(30)31)26(44)37-20(7-5-13-36-28(32)33)25(43)38-21(23(29)41)15-17-8-10-18(40)11-9-17/h8-11,16,19-22,34,40H,4-7,12-15H2,1-3H3,(H2,29,41)(H,37,44)(H,38,43)(H,39,42)(H4,30,31,35)(H4,32,33,36)/t19-,20-,21-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description
Displacement of [3H]propionyl-pNPY from human Y2 receptor expressed in CHO cells measured after 2 hrs by microbeta liquid scintillation counting anal... |
J Med Chem 63: 8198-8215 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00426
BindingDB Entry DOI: 10.7270/Q22R3W7V |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50542862
(CHEMBL4642345)Show SMILES CN[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C28H49N11O5/c1-16(2)14-22(39-24(42)19(34-3)6-4-12-35-27(30)31)26(44)37-20(7-5-13-36-28(32)33)25(43)38-21(23(29)41)15-17-8-10-18(40)11-9-17/h8-11,16,19-22,34,40H,4-7,12-15H2,1-3H3,(H2,29,41)(H,37,44)(H,38,43)(H,39,42)(H4,30,31,35)(H4,32,33,36)/t19-,20-,21-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description
Displacement of [3H]UR-MK299 from Y1 receptor in human SK-N-MC cells |
J Med Chem 63: 8198-8215 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00426
BindingDB Entry DOI: 10.7270/Q22R3W7V |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50542862
(CHEMBL4642345)Show SMILES CN[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C28H49N11O5/c1-16(2)14-22(39-24(42)19(34-3)6-4-12-35-27(30)31)26(44)37-20(7-5-13-36-28(32)33)25(43)38-21(23(29)41)15-17-8-10-18(40)11-9-17/h8-11,16,19-22,34,40H,4-7,12-15H2,1-3H3,(H2,29,41)(H,37,44)(H,38,43)(H,39,42)(H4,30,31,35)(H4,32,33,36)/t19-,20-,21-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| <3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description
Displacement of [3H]UR-MK299 from Y1 receptor in human SK-N-MC cells |
J Med Chem 63: 8198-8215 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00426
BindingDB Entry DOI: 10.7270/Q22R3W7V |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50542862
(CHEMBL4642345)Show SMILES CN[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C28H49N11O5/c1-16(2)14-22(39-24(42)19(34-3)6-4-12-35-27(30)31)26(44)37-20(7-5-13-36-28(32)33)25(43)38-21(23(29)41)15-17-8-10-18(40)11-9-17/h8-11,16,19-22,34,40H,4-7,12-15H2,1-3H3,(H2,29,41)(H,37,44)(H,38,43)(H,39,42)(H4,30,31,35)(H4,32,33,36)/t19-,20-,21-,22-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description
Displacement of [3H]propionyl-pNPY from human Y5 receptor expressed in human HEC1B cells |
J Med Chem 63: 8198-8215 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00426
BindingDB Entry DOI: 10.7270/Q22R3W7V |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50542862
(CHEMBL4642345)Show SMILES CN[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C28H49N11O5/c1-16(2)14-22(39-24(42)19(34-3)6-4-12-35-27(30)31)26(44)37-20(7-5-13-36-28(32)33)25(43)38-21(23(29)41)15-17-8-10-18(40)11-9-17/h8-11,16,19-22,34,40H,4-7,12-15H2,1-3H3,(H2,29,41)(H,37,44)(H,38,43)(H,39,42)(H4,30,31,35)(H4,32,33,36)/t19-,20-,21-,22-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description
Displacement of [3H]propionyl-pNPY from human Y5 receptor expressed in human HEC1B cells |
J Med Chem 63: 8198-8215 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00426
BindingDB Entry DOI: 10.7270/Q22R3W7V |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50542862
(CHEMBL4642345)Show SMILES CN[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C28H49N11O5/c1-16(2)14-22(39-24(42)19(34-3)6-4-12-35-27(30)31)26(44)37-20(7-5-13-36-28(32)33)25(43)38-21(23(29)41)15-17-8-10-18(40)11-9-17/h8-11,16,19-22,34,40H,4-7,12-15H2,1-3H3,(H2,29,41)(H,37,44)(H,38,43)(H,39,42)(H4,30,31,35)(H4,32,33,36)/t19-,20-,21-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.18E+3 | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description
Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB2 assessed as induction of beta-arrestin2 recruitment measured for 40 mins... |
J Med Chem 63: 8198-8215 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00426
BindingDB Entry DOI: 10.7270/Q22R3W7V |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50542862
(CHEMBL4642345)Show SMILES CN[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C28H49N11O5/c1-16(2)14-22(39-24(42)19(34-3)6-4-12-35-27(30)31)26(44)37-20(7-5-13-36-28(32)33)25(43)38-21(23(29)41)15-17-8-10-18(40)11-9-17/h8-11,16,19-22,34,40H,4-7,12-15H2,1-3H3,(H2,29,41)(H,37,44)(H,38,43)(H,39,42)(H4,30,31,35)(H4,32,33,36)/t19-,20-,21-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description
Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB2 assessed as induction of beta-arrestin2 recruitment measured for 40 mins... |
J Med Chem 63: 8198-8215 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00426
BindingDB Entry DOI: 10.7270/Q22R3W7V |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50542862
(CHEMBL4642345)Show SMILES CN[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C28H49N11O5/c1-16(2)14-22(39-24(42)19(34-3)6-4-12-35-27(30)31)26(44)37-20(7-5-13-36-28(32)33)25(43)38-21(23(29)41)15-17-8-10-18(40)11-9-17/h8-11,16,19-22,34,40H,4-7,12-15H2,1-3H3,(H2,29,41)(H,37,44)(H,38,43)(H,39,42)(H4,30,31,35)(H4,32,33,36)/t19-,20-,21-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.46E+3 | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description
Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB1 assessed as induction of beta-arrestin1 recruitment measured for 40 mins... |
J Med Chem 63: 8198-8215 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00426
BindingDB Entry DOI: 10.7270/Q22R3W7V |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50542862
(CHEMBL4642345)Show SMILES CN[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C28H49N11O5/c1-16(2)14-22(39-24(42)19(34-3)6-4-12-35-27(30)31)26(44)37-20(7-5-13-36-28(32)33)25(43)38-21(23(29)41)15-17-8-10-18(40)11-9-17/h8-11,16,19-22,34,40H,4-7,12-15H2,1-3H3,(H2,29,41)(H,37,44)(H,38,43)(H,39,42)(H4,30,31,35)(H4,32,33,36)/t19-,20-,21-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description
Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB1 assessed as induction of beta-arrestin1 recruitment measured for 40 mins... |
J Med Chem 63: 8198-8215 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00426
BindingDB Entry DOI: 10.7270/Q22R3W7V |
More data for this
Ligand-Target Pair | |