Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 288.3 BDBM378831

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM378831 (5-cyclopropyl-N-((1R,3r,5S)-8-methyl-8-azabicyclo[...) Show SMILES CN1[C@H]2CC[C@@H]1C[C@@H](C2)NC(O)c1cc(cnn1)C1CC1 |r,TLB:0:1:4.3:7.6.8| Show InChI InChI=1S/C16H24N4O/c1-20-13-4-5-14(20)8-12(7-13)18-16(21)15-6-11(9-17-19-15)10-2-3-10/h6,9-10,12-14,16,18,21H,2-5,7-8H2,1H3/t12-,13+,14-,16?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...				Bioorg Med Chem 14: 7241-57 (2006) BindingDB Entry DOI: 10.7270/Q2DJ5HX2
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