Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 425.4 BDBM372465

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372465 (N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...) Show SMILES CN1C(=O)C(C)(C)c2cc(CC(=O)Nc3cnn(Cc4ccc(F)c(F)c4)n3)ccc12 Show InChI InChI=1S/C22H21F2N5O2/c1-22(2)15-8-13(5-7-18(15)28(3)21(22)31)10-20(30)26-19-11-25-29(27-19)12-14-4-6-16(23)17(24)9-14/h4-9,11H,10,12H2,1-3H3,(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair