Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 412.5 BDBM363981

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363981 (US9856250, 24) Show SMILES CN1C=C(C2C=CC=CC12)C(=O)NC[C@H]1C[C@@H]2CC[C@H](C1)N2CC(=O)NC(C)(C)C |r,c:2,5,7,THB:22:21:20.14.15:17.18| Show InChI InChI=1S/C24H36N4O2/c1-24(2,3)26-22(29)15-28-17-9-10-18(28)12-16(11-17)13-25-23(30)20-14-27(4)21-8-6-5-7-19(20)21/h5-8,14,16-19,21H,9-13,15H2,1-4H3,(H,25,30)(H,26,29)/t16-,17-,18+,19?,21?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair